I think the “guard rail” concept (or if you prefer “training wheels”, though people may take that to be pejorative) is the biggest reason so many aspiring shredders use a choked up grip and profess love for small picks like the “standard” Jazz III.
I think “training wheels” is really apt, because used properly, training wheels aren’t meant to be in constant contact with the ground. Rather, they’re meant to save you from falling if you go off balance (or off “center” if you will). A choked up pick grip provides tactile feedback if you attempt a motion that would result in a “deeper than intended” pickstroke.
Note that I’m not saying that’s what people should do. I’m merely observing that I think it’s why a lot of people decide they want to use that style of grip (or why they like a small pick), even if they can’t articulate how it’s helping them.
I do think that in general, some kind of tactile feedback or and/or “reference bracing” can help people pick with consistent depth (and perhaps even train their muscles to make a movement that produces pickstrokes with consistent depth). For example, I think some players accomplish this with contact of the wrist or heel of the thumb against the strings, the guitar face or the bridge. Fingers on the guitar face (typically in the pickguard area) can accomplish this too.
As one particular example, I think the way Michael Angelo Batio braces his fingers against the guitar face is a key to his ability to have very fast and consistent pickstrokes, even with an aggressive attack. In fact, I think MAB’s approach to fast alternate picking also overcomes the “string deflection problem”, because the way his arm is arched and fingers braced creates a rigid frame where he is “sinking” downward force that is opposed by the normal force of the guitar face, and any upward force of the strings against the pick is overcome by the surplus of downward force his arm has as it presses against the guitar face. Not that he has to press incredibly hard, but by applying even slight/moderate pressure in support of the arched arm, he can produce a picking motion that won’t be perturbed significantly by resistance from the string.