How to pick this John Mayer Lick

Hi all - how do you recommend to pick this John Mayer lick? He seems to be alternate picking every note if my ears don’t deceive me. Thanks!

That’s very SRV-ish. I would try to go for a mix of picking and blues hammer-ons/pull-offs, especially focusing on keeping a steady rhythm with the picking hand (I mean rhythm as in “groove”, not any specific group of picked notes).