If we’re excluding the possibility of relocating the notes on the fretboard, I would left hand finger as
1 1 3 2
1 1 3 2
1 1 …and then end with one of these
212 or
213 or
312
I don’t have my guitar on me at the moment so not sure which ending would be best.
It’s important to not use the same finger for two notes in a row if they are on different strings AND different frets, imo, which is why I would not go 1121 1121
The right hand option that would be easiest for me personally would probably be
MUUI repeated basically, but there are a few different configurations that could work with hybrid picking. I’m a “downslanter” by habit so I’d also like MUDD
If we’re allowing relocation, a lot of things become possible. One option is to do @Riffdiculous ’s arrangements but with those B string notes on the high E, and go with the picking hand maybe middle finger then two pick strokes then a slur. On paper it looks harder with the stretch but I personally have an easier time stretching sometimes rather than jamming fingers 3 and 4 on the same fret or trying to roll either finger.