My guitar’s neck has a radius and normaly i would set my string height following the radius, and because of that the strings in the middle are somewhat higher thee the lower and higher strings.
As an expiriment i now put the lower and higher strings to the same hight as the middle strings.
I always try to hit the strings with as less of the pick as possible and always have the feeling i had to compensate the path the pick follows due to the difference in string height.
Now it feels easier hitting every strings with the same amount of pick.
Downside is of course that you have to get used to the somewhat higher action on the lower and higher strings.
I am not sure yet if leave it this way, but sofar it feels good.