There’s not a different radius to different wrist motions — the pick is just as far away from the fulcrum going up and down as it is going side to side. If I’m understanding you correctly.
I think the difference is neuro-muscular of some sort. The muscles involved in doing flexion-extension are just stupid fast. Ran across this example today. But if you’ve ever done fretboard tapping with a pick using your wrist, you’ve probably already experienced how crazy fast it is: